The Role of Sialic Acid in the Release of Proteins from L1210 Leukemia Cells1
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چکیده
The presence of sialic acid on cell membranes was found to be necessary for the outward flow of proteins from L1210 leu kemia cells. The removal of membrane-bound sialic acid inhib ited the release of proteins without any effect on cell lysis, or on the release of nucleotides or sugars. The requirement for sialic acid in promoting protein secretion seemed relatively specific for certain proteins, as determined by means of disc gel electrophoresis.
منابع مشابه
The role of sialic acid in the release of proteins from L1210 leukemia cells.
The presence of sialic acid on cell membranes was found to be necessary for the outward flow of proteins from L1210 leu kemia cells. The removal of membrane-bound sialic acid inhib ited the release of proteins without any effect on cell lysis, or on the release of nucleotides or sugars. The requirement for sialic acid in promoting protein secretion seemed relatively specific for certain protein...
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تاریخ انتشار 2006